Wembanyama shot 9 of 13 from the field, including 3 of 6 from three-point range, and added seven rebounds and three assists before sitting out the fourth quarter with the other four Spurs starters, according to the Associated Press. Devin Vassell added 15 points for San Antonio.
The Spurs led by 15 points at halftime and then erupted for 45 points in the third quarter, shooting 18 of 27 from the field in the period, according to Field Level Media. Wembanyama scored 13 points in the quarter, and San Antonio led by as many as 35 points and never trailed in the game.
The score was 109-76 entering the fourth quarter, and San Antonio led comfortably throughout the final period despite sitting all of its starters, according to Field Level Media. The Spurs outrebounded Portland 51-38 and made 28 of 30 free-throw attempts.
The win improved San Antonio to 8-2, while Portland fell to 6-3, according to the Associated Press. It was the Spurs' most dominant win of the season so far, and their third straight win on the second night of a back-to-back.
San Antonio's winning streak is the longest active run in the league, and the Spurs now travel to Phoenix to play the Suns on Monday, according to the Associated Press.
Sources: Associated Press (via theScore); Field Level Media